What is an
allergic
reaction?

All devices shown are not actual size.
All patients shown are actor portrayals.

No time to wait.
No time to hesitate.

Millions of people have allergies to foods, insect stings or bites, medicines, or exercise.* Sometimes the cause of the allergic reaction is unknown. These allergic reactions are serious and can lead to anaphylaxis, which is potentially life-threatening, within minutes of exposure to an allergen.

Be neffy ready. Fill out the step-by-step Action Plan so that you, and those close to you, know exactly what to do during, and after a reaction.

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Food

Exercise

Insect
Venom

Medicines
& Latex

*Not a complete list of all possible allergens. Allergies are individual to each person.

What are the symptoms of an allergic reaction?

Within minutes of exposure to an allergen, people can experience one or more symptoms affecting different parts of the body and at varying levels of severity. Treat with epinephrine as soon as you notice any of the symptoms below. Don't hesitate, as the reaction can become more severe quickly.

Skin & mouth

Skin & mouth

  • Hives or raised, itchy bumps
  • Redness
  • Itching
  • Swelling of the lips or tongue
Breathing

Breathing

  • Trouble breathing
  • Shortness of breath
  • Tight throat, hoarsenness, or trouble swallowing
  • Wheezing
  • Coughing
Circulation

Circulation

  • Dizziness or fainting
  • Weak pulse
  • Pale or bluish skin color
Other symptoms

Other symptoms

  • Nausea, vomiting, or diarrhea
  • Feelings of "doom," confusion, altered consciousness, or agitation

Every second counts

83% of people hesitate or don’t use epinephrine during an allergic reaction, increasing the risk of serious complications.

Will you have epinephrine when you need it?

neffy epinephrine nasal spray devices
Allergic reactions can be unpredictable. But approximately 60% of patients do not consistently carry their epinephrine needle-injectors, possibly because some have a fear of needles.

neffyconnect makes it easier than ever to stay prepared

Always carry neffy, the only needle-free epinephrine nasal spray, and stay neffy ready with expiration reminders, support, and education with neffyconnect. Sign up for refill reminders, emails and texts to stay informed and ready.

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Get to know
neffy

Learn more

WHAT IS neffy?

neffy is a nasal spray used for emergency treatment of allergic reactions including anaphylaxis, in adults and children aged 4 years and older who weigh 33 lbs or greater.

IMPORTANT SAFETY INFORMATION

What is the most important information that I should know about neffy?

neffy contains epinephrine, a medicine used to treat allergic emergencies (anaphylaxis). Anaphylaxis can be life-threatening, can happen in minutes, and can be caused by stinging and biting insects, allergy injections, foods, medicines, exercise, or other unknown causes.

Always carry two neffy nasal sprays with you because you may not know when anaphylaxis may happen and because you may need a second dose of neffy if symptoms continue or come back. Each neffy contains a single dose of epinephrine. neffy is for use in the nose only.

Use neffy right away, as soon as you notice symptoms of an allergic reaction. If symptoms continue or get worse after the first dose of neffy, a second dose is needed. If needed, administer a second dose using a new neffy in the same nostril starting 5 minutes after the first dose. Get emergency medical help for further treatment of the allergic emergency (anaphylaxis), if needed after using neffy.

Tell your healthcare provider if you have underlying structural or anatomical nasal conditions, about all the medicines you take, and about all your medical conditions, especially if you have heart problems, kidney problems, low potassium in your blood, Parkinson's disease, thyroid problems, high blood pressure, diabetes, are pregnant or plan to become pregnant, or plan to breastfeed.

Tell your healthcare provider if you take or use other nasal sprays or water pills (diuretics) or if you take medicines to treat depression, abnormal heart beats, Parkinson's disease, heart disease, thyroid disease, medicines used in labor, and medicines to treat allergies. neffy and other medications may affect each other, causing side effects. neffy may affect the way other medicines work, and other medicines may affect how neffy works.

What are the side effects of neffy?

neffy may cause serious side effects. If you have certain medical conditions or take certain medicines, your condition may get worse, or you may have more or longer lasting side effects when you use neffy.

Common side effects of neffy include: nasal discomfort, headache, throat irritation, chest and nasal congestion, feeling overly excited, nervous or anxious, nose bleed, nose pain, sneezing, runny nose, dry nose or throat, tingling sensation, including in the nose, feeling tired, dizziness, nausea, and vomiting.

Tell your healthcare provider if you have any side effects that bother you or that do not go away after using neffy.

These are not all of the possible side effects of neffy. Call your healthcare provider for medical advice about side effects. To report side effects, contact ARS Pharmaceuticals Operations, Inc. at 1-877-MY-NEFFY (877-696-3339) or the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Please see the full Prescribing Information and Patient Information for neffy.

ARS Pharmaceuticals Operations, Inc. website

© 2025 ARS Pharmaceuticals Operations, Inc. All rights reserved. “ARS Pharma,” the ARS Pharma logo design, “neffy,” the neffy logo, and the neffyconnect logo are trademarks or registered trademarks of ARS Pharmaceuticals Operations, Inc. All other trademarks are the property of their respective owners. NEF-US-0046-13 | 06/2025